Our Research
Our goal is to improve human health by defining the underlying principles that control human biology and disease. Towards this goal, we develop and employ powerful new genomic technologies that show us how human disease develops, and how we can target the underlying causes. The technologies we use include CRISPR genome editing, single cell genomics, transgenic animals (flies and mice), and human stem cells differentiated into human cells, tissues, and organoids. Together these approaches let us investigate the genes and underlying mechanisms that control human biology and health.
The specific genes we investigate are continually evolving as we learn more about the human genome, currently we are focused on these major areas:
