Functional Genomics
Our goal is to improve human health by defining the underlying principles that control human biology and disease. Towards this goal, we develop and employ powerful new genomic technologies that show us how human disease develops, and how we can target the underlying causes. The technologies we use include CRISPR genome editing, single cell genomics, transgenic animals (flies and mice), and human stem cells differentiated into human cells, tissues, and organoids. Together these approaches let us investigate the genes and underlying mechanisms that control human biology and health.
Currently we have a major focus on the genomics of chronic pain, however we have projects that relate to heart function, neurodegeneration, lifespan and metabolic disorders, kidney function, and cancer. Our interests are flexible and depend on the experience and interests of our team. In the end our goal is to rapidly improve patient treatment, and many of the new genes we have identified appear to be viable drug targets.
University of Sydney
The Neely Lab is based in the Charles Perkins Centre, which was completed in June 2014, and offers state-of-the-art facilities. The Neely Lab and the Charles Perkins Centre are affiliated with the University of Sydney's (USYD) Camperdown campus. USYD has over 50000 students spread across multiple campuses within Sydney, Australia. USYD was the first university to be established in Australia in the 1850’s and is currently ranked as the world’s 20th most reputable university and its graduates are considered the 4th most employable in the world.*
*CPC photo by Jason Tong click here